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KMID : 1134820070360121523
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Journal of the Korean Society of Food Science and Nutrition
2007 Volume.36 No. 12 p.1523 ~ p.1528
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Antioxidative Effects of Mugwort (Artemisia vulgaris L.) Extracts Diet on ICR Mouse Skin
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Park Si-Hyang
Choi Gyeong-Lim
Choi Yeung-Joon
Choi Jin-Ho
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Abstract
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The feeding effects of mugwort (Artemisia vulgaris L.) extracts (ME) on the anti-oxidative actions of ICR mouse skin was investigated. To study the antioxidative effects of ME on ICR mouse skin, female ICR mice were grouped into basic diet group (control), ascorbic acid diet group (AA-2.5, AA-5.0, AA-10.0 and AA-20.0 ㎎/㎏ BW/day) as a positive control and experimental diet group (mugwort extract; ME-25, ME-50, ME-100, and ME-200 ㎎/㎏ BW/day) and fed for 10 weeks. Protein contents in ME-50, ME-100, and ME-200 feeding group were increased (3.1%～11.1%) and hydroxyl radical contents were significantly decreased (10.4%～17.4%) compared to control group. Oxidative stress signals and oxidized protein contents were significantly reduced to the range of 15.3 to 17.1% in ME-100 and ME-200 groups. Also, superoxide dismutase (SOD) activity was significantly increased to the range of 15.0% to 23.3% in ME-100 and ME-200 groups. Catalase activities were significantly increased (14.0%～36.9%) in all groups in a dose-dependent pattern. Antioxidative ability of ME showed similarity to that of ascorbic acid.
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KEYWORD
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mugwort (Artemisia vulgaris L.) extract, ascorbic acid, antioxidative effect, skin
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